Keywords; pfizer bextra, arthritis, anti inflammatory drugs, NSAIDs.
This finding against a major pharmaceutical company confirms the danger of COX 2 inhibitors associated with cardiovascular, gastrointestinal bleeding and serious skin reactions.
COX 2 inhibitors have been purported to be the new wonder drug for arthritis another painful inflammatory conditions, but not having the serious gastrointestinal side effects. It's widely acknowledged that more than 12 000 people die annually in the USA from gastric bleeds directly associated with NSAID drugs.
COX 2 wouldn't do that.
However, it soon became apparent that COX 2 inhibitors had serious side effects on the cardiovascular system. VIOXX was immediately withdrawn from the market, for example.
PFIZER was allowed to continue marketing BEXTRA IN VERY LIMITED DOSES for conditions such as menstrual cramps and arthritis. In conflict with the FDA regulations, Pfizer promoted BEXTRA using an illegal technique called "off-labeling" for uses and in doses that far exceeded that approved by the FDA.
This put patients at risk from MI (heart attack), CVA (stroke) and pulmonary embolism.
On 2 September 2009, Pfizer agreed to pay $2.3 billion in criminal fines and civil charges. Pfizer Bextra is the name we now associate with major fraud.
The FDA has now demanded that all anti inflammatory drugs manufacturers must label
their products with warnings about
"increased risk of cardio-vascular events and well-described, serious, and potentially life-threatening gastro-intestinal bleeding associated with their use."
Aside: Anti-inflammatory drugs such as Pfizer Bextra are particularly dangerous when taken in association with other drugs, even aspirin. So-called Dual Antiinflammatory Drugs is something to be avoided at all costs.
Chiropractors are not in principle against the lawful and sensible short-term use of NSAIDs, but we believe there is now overwhelming evidence that manual methods and exercise have far more benefits with none of the side effects of these dangerous medicines in the treatment of many Chiropractic Conditions and forms of arthritis.
In addition there is overwhelming evidence that many foods have an anti inflammatory effect. The oleocanthal found only in olives and extra virgin olive oil, for example, also acts as a Cox 2 inihibitor but by a completely different mechanism to the anti inflammatory drugs, and without the side effects.
Just one of the many Olive Oil benefits enjoyed primarily by the Mediterranean people.
It's also been clearly demonstrated that a diet high in omega-6 fatty acids, but low in omega-3 is strongly pro-inflammatory. Read, those who have a diet high in seed oils but low in fatty fish, olive oil, nuts, flaxseed and avocado are at high risk of generalised inflammation in the body affecting joints, muscles, blood vessels and really all tissue.
Simple dietary changes such as generously dribbling extra virgin olive oil instead of using a branded salad dressing, almost always based on sunflower, sprinkling freshly ground flax seeds on a muesli, and enjoying fatty fish at least twice a week would make a profound change for the better for many inflammatory conditions.
Whilst natural foods have a much lower potency than drugs, enjoyed in the diet every day, they are perfectly safe, far cheaper and have none of the side effects of medication.
Ever heard of anyone dropping dead from dribbling extra virgin olive oil on their salad? Or having a heart attack after enjoying salmon or mackerel for dinner?
Even the capaicin in jalapenos and the omega 3 in freshly ground flaxseeds have proven anti inflammatory properties.
Enjoying daily anti inflammatory foods is an important part of the the way to get your arteries, muscles and joints into shape. Let your food be your medicine.
Many insurance companies now only pay for physical therapists to provide a chiropractic adjustment; that's in the face of powerful research proving that inclusion of DCs to perform their own technique would save them a good deal of money. One has to conclude that political medicine has gone off on another tack to contain our profession.
It's being successful with some doctors of chiropractic quitting. Others become involved in some dodgy practices, like demanding that patients sign up for a whole year of treatment in advance, in order to stay in business.
In recessionary times, the going is tough when the insurance won't pay.
Is the day approaching for a new Wilk versus the AMA and the insurance companies?
The chiropractic profession has tried hard to stay on the moral high ground; those who stoop to unscrupulous practices need to be exposed and disciplined if we are not to stoop to the low blows that medicine has often resorted to contain and eliminate us.
Chiropractic Books.com and its two sister sites Chiropractic Help.com and Bernard Preston.com bring you plenty of information about new books, care of the body, and healthy living tips from your own vegetable and fruit gardening, to flaxseed for omega 3 and much more.